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localized prostate cancer treatment options
  • Incidenta prostatitei
  • prostate cancer - Translation into Romanian - examples English | Reverso Context
  • Source: Romanian Medical Journal.
  • Complications from prostate cancer can arise when it metastasizes.

There is a discrepancy in the Gleason score given on the initial biopsy and prostatectomy specimen, respectively, that affects both patients who can benefit from active surveillance and those who cannot benefit from curative surgical treatment, and for whom therapeutic alternatives must be established.

In this context, our study aimed at analyzing the diagnostic concordance between biopsies and subsequent prostatectomies, in order to establish the accuracy of prostate biopsy in predicting final Gleason score of the prostatectomy specimens.

Material and methods: We analyzed 79 cases of PADK, initially diagnosed by prostate biopsy and subsequently treated by radical prostatectomy.

  • Usturime la urinare cauze
  • Prostate Cancer: Diagnosis and Clinical Management - radioteca.ro
  • Do you manage patients with prostate cancer?
  • Metastatic cancer prostate treatment Conținutul Do you manage patients with prostate cancer?

The accuracy degree of the tumoral grading system assigned to the prostate biopsy, compared with the radical prostatectomy, was assessed by calculation of the Cohen's kappa concordance coefficient and calculation of sensitivity, specificity, positive prognostic value and negative prognostic value. Results: 37 cases In prostate biopsies, 32 cases localized prostate cancer treatment options The lowest agreement rate was observed for Gleason score 5, where no case showed a similar score for biopsy and prostatectomy.

Prostate Cancer: Diagnosis and Clinical Management

Statistical analysis indicated a kappa coefficient of 0. The agreement on ISUP prognostic grade groups between prostate biopsy and radical prostatectomy indicated a slight increase in kappa coefficient Conclusions: Our results demonstrate an increase in the predictive accuracy of prostate biopsy, as a result of the application of prognostic grade group localized prostate cancer treatment options, which ensure the decrease of overestimating tendency of the old scoring system, ultimately leading to a preliminary characterization of potential lesions in prostatectomy specimens and a more effective treatment stratification of patients.

Voichiţa Bar Ad, M. The clinically negative neck of the patients with HNSCC may be managed with observation only, elective neck dissection or elective radiation therapy. There are no large prospective randomized trials comparing between these treatment options. The principal aim of treating electively the clinically negative neck in patients with HNSCC, by ei­ther surgery or radiation therapy is to maximize the rate of control of the disease in the neck. It remains to be proven if the elective neck treatment contributes to improved overall survival for the patients with HNSCC and clinically negative neck.

Author Biographies A. Lyon: International Agency for Research on Cancer, A contemporary prostate cancer grading system: A vali-dated alternative to the Gleason score.

Eur Urol ; 69 3 : Gleason DF. Classification of prostatic carcinomas.

  1. -- думалось .
  2. Prostatitis bacteriana aguda en perros

Cancer Chemother Rep ; 50 3 Prediction of prognosis for prostatic adenocarcinoma by combined histo-logical grading and clinical staging. J Urol ; 1 : Histological grading and staging of prostatic carcinoma.

BRAHITERAPIA -- METODĂ CURATIVĂ ÎN CANCERUL LOCALIZAT DE PROSTATĂ.

Philadephia: Lea and Feibiger, Histologic grading of prostate cancer: a perspective. Hum Pathol ; 23 3 : Am J Surg Pathol ; 29 9 : J Clin Oncol ; 27 21 : J Urol ; 6 : — Epstein JI. An update of the Gleason grading system.

Nowadays, most cases are detected and treated at an early stage, when the tumor is still localized within the prostate. Mathematical oncology is a new trend that can contribute to overcome these issues. This approach relies on the use of mathematical models and computer simulations to predict clinical outcomes and design optimal treatments on a patient-specific basis. In this context, I will present mathematical models to describe the evolution of organ-confined prostatic tumors based on key mechanisms and I will show relevant simulations both in experimental setups and organ-scale, patient-specific scenarios. As the development of this disease can be interpreted as an evolving interface problem between healthy and tumoral tissue, these models are based on the phase-field method to account for the coupled dynamics of both tissues.

Helpap B, Egevad L. Modified Gleason grading. An updated review. Histol Histopathol ; 24 5 : Eur Urol ; 58 3 : Arch Pathol Lab Med ; 4 : The impact of the Interna-tional Society of Urological Pathology Gleason grading consensus on active surveillance for prostate cancer.

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Cent European Localized prostate cancer treatment options Urol ; 70 4 : Upgrading and upstaging in prostate cancer: From prostate biopsy to radical prostatectomy. Mol Clin Oncol ; 2 6 : J Clin Oncol ; 34 18 : Front Med Lausanne ; 4: Prostate cancer grading: a decade after the modified system. Mod Pathol ; 31 S1 : SS Grignon DJ. Prostate cancer reporting and staging: needle biopsy and radical prostatectomy specimens. Preoperative prediction of Gleason grade in radical prostatectomy specimens: the influence of different Gleason grades from multiple positive biopsy sites.

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Mod Pathol ; 18 2 : Evaluation of concordance of Gleason score between prostatectomy and biopsies that show more than two different Gleason scores in positive cores. Urology ; 67 1 : Multiple prostate cancer cores with different Gleason grades submitted in the same specimen container without specific site designation: should each core be assigned an individual Gleason score?

Hum Pathol ; 40 4 : Should intervening benign tissue be included in the meas-urement of discontinuous foci of cancer on prostate needle biopsy?

Treatment Options for Localized Prostate Cancer

Correlation with radical prostatec-tomy findings. Am J Surg Pathol ; 35 9 : Continuous versus discontinuous tumor involvement: A di-lemma in prostate biopsy quantitation. Prostate ; 78 15 : Prognostic value of percent Gleason grade 4 at prostate biopsy in predicting prostatectomy pathology and recurrence.

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